Ensiklopedia

MTOR
Struktur yang tersedia
PDB	Pencarian Ortolog: PDBe RCSB
Daftar kode id PDB
	4JT6 , 1AUE , 1FAP , 1NSG , 2FAP , 2GAQ , 2NPU , 2RSE , 3FAP , 4DRH , 4DRI , 4DRJ , 4FAP , 4JSN , 4JSP , 4JSV , 4JSX , 4JT5 , 5FLC
Pengidentifikasi
	MTOR , FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS, mechanistic target of rapamycin, mechanistic target of rapamycin kinase
ID eksternal	601231 1928394 3637 MTOR
Pola ekspresi RNA
	Referensi data ekspresi selengkapnya
Fungsi molekuler	• protein domain specific binding ; • TFIIIC-class transcription factor complex binding ; • kinase activity ; • ATP binding ; • protein serine/threonine kinase activity ; • transferase activity ; • ribosome binding ; • GO:0001948, GO:0016582 Ikatan protein plasma ; • protein kinase binding ; • nucleotide binding ; • phosphoprotein binding ; • protein kinase activity ; • GO:0032403 protein-containing complex binding ; • pengikatan protein identik ; • translation regulator activity ;
Komponen seluler	• sitoplasma ; • sitosol ; • phosphatidylinositol 3-kinase complex ; • membran ; • mitokondria ; • TORC1 complex ; • organelle membrane ; • GO:0009327 protein-containing complex ; • mitochondrial outer membrane ; • Retikulum endoplasma ; • TORC2 complex ; • badan Golgi ; • intracellular membrane-bounded organelle ; • nucleoplasm ; • soma ; • PML body ; • endoplasmic reticulum membrane ; • Golgi membrane ; • lysosomal membrane ; • Dendrit ; • Sistem endomembran ; • Inti sel ; • Lisosom ; • glutamatergic synapse ; • postsynaptic cytosol ;
Proses biologis	• germ cell development ; • positive regulation of protein phosphorylation ; • response to amino acid ; • positive regulation of lipid biosynthetic process ; • positive regulation of actin filament polymerization ; • positive regulation of skeletal muscle hypertrophy ; • positive regulation of granulosa cell proliferation ; • regulation of carbohydrate utilization ; • post-embryonic development ; • positive regulation of dendritic spine development ; • positive regulation of translation ; • positive regulation of eating behavior ; • protein phosphorylation ; • mRNA stabilization ; • cell projection organization ; • regulation of glycogen biosynthetic process ; • positive regulation of cell growth involved in cardiac muscle cell development ; • positive regulation of neuron maturation ; • positive regulation of glial cell proliferation ; • respons seluler terhadap hipoksia ; • negative regulation of cell size ; • response to cocaine ; • positive regulation of protein kinase B signaling ; • cardiac muscle contraction ; • maternal process involved in female pregnancy ; • ruffle organization ; • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity ; • cardiac muscle cell development ; • positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ; • regulation of membrane permeability ; • response to insulin ; • regulation of myelination ; • regulation of fatty acid beta-oxidation ; • regulation of osteoclast differentiation ; • positive regulation of cholangiocyte proliferation ; • regulation of protein kinase B signaling ; • spinal cord development ; • positive regulation of peptidyl-tyrosine phosphorylation ; • perilaku sosial ; • protein autophosphorylation ; • negative regulation of cholangiocyte apoptotic process ; • regulation of brown fat cell differentiation ; • regulation of protein kinase activity ; • GO:0033128 negative regulation of protein phosphorylation ; • positive regulation of oligodendrocyte differentiation ; • regulation of carbohydrate metabolic process ; • regulation of actin cytoskeleton organization ; • voluntary musculoskeletal movement ; • Fosforilasi ; • multicellular organism growth ; • negative regulation of muscle atrophy ; • wound healing ; • positive regulation of neurogenesis ; • response to morphine ; • positive regulation of sensory perception of pain ; • GO:0044257 Katabolisme protein ; • 'de novo' pyrimidine nucleobase biosynthetic process ; • cellular response to nutrient levels ; • energy reserve metabolic process ; • peptidyl-threonine phosphorylation ; • positive regulation of transcription by RNA polymerase III ; • positive regulation of smooth muscle cell proliferation ; • visual learning ; • positive regulation of myotube differentiation ; • positive regulation of cell death ; • positive regulation of endothelial cell proliferation ; • negative regulation of iodide transmembrane transport ; • cardiac muscle tissue development ; • positive regulation of nitric oxide biosynthetic process ; • regulation of response to food ; • heart morphogenesis ; • positive regulation of neuron death ; • cardiac cell development ; • negative regulation of protein ubiquitination ; • brain development ; • GO:1901313 positive regulation of gene expression ; • long-term memory ; • heart valve morphogenesis ; • GO:0035404 peptidyl-serine phosphorylation ; • positive regulation of neuron projection development ; • regulation of cellular response to heat ; • positive regulation of lamellipodium assembly ; • positive regulation of stress fiber assembly ; • GO:0072468 signal transduction ; • regulation of protein phosphorylation ; • negative regulation of macroautophagy ; • anoikis ; • TOR signaling ; • GO:0100026 Reparasi DNA ; • regulation of cell size ; • negative regulation of autophagy ; • positive regulation of epithelial to mesenchymal transition ; • regulation of macroautophagy ; • cellular response to amino acid starvation ; • positive regulation of keratinocyte migration ; • cellular response to amino acid stimulus ; • cellular response to leucine ; • positive regulation of wound healing, spreading of epidermal cells ; • cellular response to leucine starvation ; • cellular response to starvation ; • TORC1 signaling ; • Pertumbuhan tanaman ; • regulation of cell growth ; • response to nutrient ; • activation of protein kinase B activity ; • T-helper 1 cell lineage commitment ; • response to activity ; • positive regulation of phosphoprotein phosphatase activity ; • negative regulation of calcineurin-NFAT signaling cascade ; • regulation of translation at synapse, modulating synaptic transmission ; • positive regulation of cytoplasmic translational initiation ; • response to nutrient levels ;
	Sumber: Amigo / QuickGO
	2475
	56717
	ENSG00000198793
	ENSMUSG00000028991
	P42345
	Q9JLN9
	NM_004958 ; NM_001386500 ; NM_001386501
	NM_020009
	NP_004949
	NP_064393
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

MTOR adalah berkas genetik pada lokasi 1p36.2 dengan ekspresi berupa enzim jenis kinase dengan aktivitas enzimatik yang terkait dengan keluarga enzim , termasuk serina/treonina kinase . ^{[

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Rujukan

^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ (Inggris) "MTOR mechanistic target of rapamycin (serine/threonine kinase) [ Homo sapiens ]" . Entrez Gene . Diakses tanggal 2010-11-03 .

Artikel bertopik gen ini adalah sebuah rintisan . Anda dapat membantu Wikipedia dengan .

[1] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[2] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] (Inggris) "MTOR mechanistic target of rapamycin (serine/threonine kinase) [ Homo sapiens ]" . Entrez Gene . Diakses tanggal 2010-11-03 .

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